About our research

Innoscience Hungary Ltd, established in 2018 by the Zágon Family Fund—the first private fund in Hungary dedicated to brain disease research—originated from the renowned Proteomics Laboratory of Eötvös Loránd University, and now incorporates researchers from the University of Szeged. Our mission is to advance OMICS research on brain disease models and human samples, focusing on the molecular and physiological mechanisms of early-stage brain diseases.We prioritize high-risk, innovative research to uncover the early, pre-symptomatic phases of brain diseases, which are often diagnosed too late. The compensatory plasticity of the brain masks these diseases until they reach advanced stages, making early detection and intervention crucial. Despite the challenges of securing funding for such high-risk research, we are committed to supporting original ideas that have the potential to revolutionize brain disease treatment.

Our team, including Dr. Gábor Juhász, Dr. Katalin Kékesi and Dr. Magor Lőrincz, has a well-documented history of scientific contributions, available in the MTMT Hungarian database. We adhere to the belief that understanding the early changes in brain diseases at the molecular, physiological, and systems biological levels is key to developing better treatments.

Innoscience Hungary Ltd aims to gather and allocate additional financial resources for high-risk brain disease research, fostering studies that explore early-stage changes. We offer exceptional technical expertise in OMICS technologies, as recommended by the European OMICS Initiative for Central European Countries, despite the absence of a government-led initiative in Hungary. Our capabilities extend to technology and knowledge transfer to pharmaceutical companies, enhancing the early phases of drug target discovery. Additionally, we continue the legacy of our predecessor, the Proteomics Laboratory, by providing a rich knowledge base and education for postdocs and PhD students in OMICS technologies and bioinformatics. Through these efforts, we aim to build a supportive, high-tech research ecosystem dedicated to uncovering and combating brain diseases.

Our aim

Our aim is to develop a supportive, intellectually impressive, and high-tech research ecosystem for postdoctoral researchers in a nonprofit company environment. We complete budget-based research funds by involving non-budget resources such as private donations and company-oriented grants, and by submitting applications to domestic and international grants. We believe that adapting research management methods we learned in the USA and Europe helps to keep talented postdocs in brain disease research by providing a safe and trustworthy career path, compensating for the anomalies of the governmental budget-based grant system, mainly the money shortage and uncertainty in timing the grant calls.

Our experience over the past decades suggests that the discontinuous and often non-overlapping scientific grant calls in Hungary make it difficult for young researchers to work on promising topics for years without serious problems in basic living conditions. The limited technological possibilities and continuous struggle for laboratory survival drive talented young researchers abroad to establish safer careers. To counter this waste of intellectual power and resources, Innoscience Hungary Ltd was established to provide a real alternative for talented researchers within Hungary.

We aim to offer exceptional technical backgrounds and skills in OMICS technologies, as proposed by the European OMICS Initiative for Central European Countries, despite the lack of a governmentally organized initiative in Hungary. We are prepared for technology and knowledge transfer to pharmaceutical companies to improve the initial phase of drug target discovery. Additionally, we provide a knowledge base and education for postdocs and PhD students in OMICS technologies and bioinformatics, continuing the groundbreaking work of our predecessor, the Proteomics Laboratory.

Skills & equipment

We offer a wide range of proteomics technologies for tissue, synaptosome, synaptic and non-synaptic mitochondria, brain and blood exosomes, as well as serum and cerebrospinal fluid samples. We are equipped to create linear amplification-ready cDNA samples from synaptosomes and patch-clamped neurons from brain slices. Our capabilities include physiological and behavioral methods for studying brain disease animal models. We have multiple electrode systems for implantation into freely moving animals, including larger laboratory animals such as cats, allowing us to combine unit recording, field potential recording, and multielectrode EEG with drug administration by microinjection and in vivo microdialysis. This allows for refined characterisation of animal models before collecting samples for OMICS studies. Additionally, our primary neuronal cell culture technologies allow us to grow and manipulate neurons in vitro, supporting studies on neuronal differentiation, growth, and pharmacological testing. We also utilize advanced behavioral analysis tools, such as the NOLDUS system, to monitor the behavior of freely moving rats and mice. These capabilities collectively enable us to explore complex biological processes and link molecular mechanisms with behavioral outcomes, supporting a wide range of advanced neuroscience research. Our team consists of six researchers and a general manager who handles grant applications and partner communications.

Business Plan

The business plan of Innoscience Hungary Ltd is to build a research ecosystem for brain disease research by attracting support from non-governmental participants of the Hungarian economy and unifying resources from both governmental and non-governmental sources. This support will enhance high-tech, OMICS-based research necessary for developing better brain disease therapies. We also aim to give support for university-based laboratories and individual researchers through joint grants.